Fewer Kids Prescribed Drugs for Depression
http://www.washingtonpost.com/wp-dyn/articles/A55371-2005Feb1.html"The number of American children taking antidepressant drugs fell sharply last year, after months of controversy over evidence that the medications increase the risk of suicidal thoughts and behavior among some children.
The steep decline among children is a dramatic reversal of a decade-long trend of soaring prescription rates for drugs such as Prozac, Paxil and Zoloft, and the pattern of the data suggests the numbers could fall even further.
Activists who had urged the Food and Drug Administration to require a black-box warning about the risks of the drugs said the drop reflects the better decisions that parents and physicians are making after being warned about the medications.
But medical groups such as the American Psychiatric Association and the American Academy for Child and Adolescent Psychiatry warned that the government had unwittingly unleashed an uncontrolled experiment that would cause many depressed children to go without treatment and ultimately lead to more suicides.
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Also, UCLA has just released the following, though it has not been picked up by news sources:
New UCLA study disputes antidepressant/suicide link
http://www.eurekalert.org/pub_releases/2005-02/uoc--nus012705.php"Challenging recent claims linking antidepressant use to suicidal behavior, a new UCLA study shows that American suicide rates have dropped steadily since the introduction of Prozac and other serotonin reuptake inhibitor (SSRI) drugs. Published in the February edition of the journal Nature Reviews Drug Discovery, the authors caution that regulatory actions to limit SSRI prescriptions may actually increase death rates from untreated depression, the No. 1 cause of suicide.
"The recent debate has focused solely on a possible link between antidepressant use and suicide risk without examining the question within a broader historical and medical context," explained Dr. Julio Licinio, a professor of psychiatry and endocrinology at the David Geffen School of Medicine and a researcher at the UCLA Neuropsychiatric Institute. "We feared that the absence of treatment may prove more harmful to depressed individuals than the effects of the drugs themselves."
"The vast majority of people who commit suicide suffer from untreated depression," he added. "We wanted to explore a possible SSRI-suicide link while ensuring that effective treatment and drug development for depression were not halted without cause."
Licinio worked with fellow psychiatrist Dr. Ma-Ling Wong to conduct an exhaustive database search of studies published between 1960 and 2004 on antidepressants and suicide. The team reviewed each piece of research in great detail and created a timeline of key regulatory events related to antidepressants. Then they generated charts tracking antidepressant use and suicide rates in the United States.
What they found surprised them.
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