2 Studies Question the Effectiveness of Flu Vaccines
By ELISABETH ROSENTHAL
Published: September 21, 2005
Rome, Sept. 21 - Just as governments around the world are stockpiling millions of doses of flu vaccine and antiviral drugs in anticipation of a potential influenza pandemic, two new research papers published today have found that such treatments are far less effective than previously thought.
"The studies published today reinforce the shortcomings of our efforts to control influenza," wrote Dr. Guan Yi, a virologist at the University of Hong Kong, in an editorial that accompanied the papers. The two studies were published early online by the British medical journal, the Lancet, because of their implications for the upcoming flu season.
In one paper, international researchers analyzed all the data from patient studies on the flu vaccine performed worldwide in the past 37 years and discovered that vaccines showed at best a "modest" ability to prevent influenza or its complications in elderly people....
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In the second paper, researchers from the Centers for Disease Control found that influenza viruses, particularly those from the dreaded bird flu strain, had developed high rates of resistance to older and cheaper antiviral drugs - rates that have escalated rapidly since 2003, particularly in Asia.
"We were alarmed to find such a dramatic increase in drug resistance in circulating human influenza viruses in recent years," said Dr. Rick Bright of the Centers for Disease Control, in Atlanta. "Our report has broad implications for agencies and governments planning to stockpile these drugs for epidemic and pandemic strains of influenza."...
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