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Edited on Tue Mar-21-06 02:08 AM by shanti
By LAURAN NEERGAARD, AP Medical Writer Mon Mar 20, 4:51 PM ET
WASHINGTON - Chronic heartburn appears to be fueling the nation's fastest-growing cancer, esophageal cancer. Some 3 million Americans are thought to have a type of esophagus damage from severe acid reflux that puts them at increased risk for the deadly cancer — and new research is exploring whether it's possible to zap away that damage and block the cancer from ever forming.
"The million-dollar question is can we prevent cancer," says Dr. V.K. Sharma of the Mayo Clinic in Scottsdale, Ariz., who is leading one of the newest studies, using radiofrequency energy to burn away the damage. "That has not been answered."
But it's a question taking on new urgency as doctors chart a six-fold increase in the last two decades in the main type of esophageal cancer.
About 14,550 Americans will be diagnosed with esophageal cancer this year, the American Cancer Society estimates. Most won't be diagnosed until they feel such symptoms as trouble swallowing and loss of appetite. The prognosis is grim: Just 16 percent of esophageal cancer patients survive five years, and 13,770 are predicted to die this year.
Most have esophageal adenocarcinoma, the type linked to severe chronic heartburn.
With this "gastroesophageal reflux disease," or GERD, a loose valve allows stomach acid to regularly back up into the delicate esophagus. In a fraction of heartburn sufferers, most over age 50, severe GERD over many years actually changes the lining of the esophagus: When the stomach acid kills cells in that lining, the esophagus eventually starts healing itself with more acid-resistant cells — which happen to be cancer-prone.
*snip*
on a related note from a bit ago...ann richards was recently diagnosed with esophageal cancer. it seems to be rising. my uncle has it too.
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