Los Angeles Daily News
Many study results fail to hold up
By Associated Press
Wednesday, July 13, 2005 - CHICAGO -- Here's some medical news you can trust: A new study confirms that what doctors once said was good for you often turns out to be bad -- or at least not as great as initially thought.
The report is a review of major studies published in three influential medical journals between 1990 and 2003, including 45 highly publicized studies that initially claimed a drug or other treatment worked.
Subsequent research contradicted results of seven studies -- 16 percent -- and reported weaker results for seven others, an additional 16 percent. That means nearly one-third of the original results did not hold up, according to the study in Wednesday's Journal of the American Medical Association.
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Experts say the study is a reminder to doctors and patients that they should not put too much stock in a single study and understand that treatments often become obsolete with medical advances.
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Ioannidis' study examined research in the New England Journal of Medicine, Lancet and JAMA.
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