Governments of the 13 countries where tigers still live aim to agree moves that could double numbers of the endangered big cats within 12 years.
The International Tiger Conservation Forum in St Petersburg will discuss proposals on protecting habitat, tackling poaching, and finance.
About 3,000 tigers live in the wild - a 40% decline in a decade.
There are warnings that without major advances, some populations will disappear within the next 20 years.
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Film star Jackie Chan recently voiced some public service announcements in China asking people not to use tiger parts, which Mr Zoellick said was playing a part in "chan{g}ing public attitudes".
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