If you're planning on moving to Pdx, consider the Eastside. It is more affordable and there are plenty of happening areas. NE Portland was awfully scary 15 years ago, but now it is full of families and artsy places. Either SE or NE are great places. Some will say N Portland, but I wouldn't only because I am less familiar with that area. I like SE up to about SE 60th and not any farther south than Powell Blvd, and NE up to oh, not any farther north than Columbia Blvd or so. There are wonderful walking areas around Hawthorne Blvd between downtown and 60th, and NE Alberta Street is pretty cool too.
The Pearl is a wonderful place, but far too expensive. Don't get sucked into the suburbs of Gresham, Hillsboro or Beaverton. Just because they are on the public transportation lines doesn't make them wonderful places to live. (No offense intended towards DUers that happen to live there.)
Check oregonlive.com for job listings.
http://www.oregonlive.com/jobs/They also have a rental section.
http://realestate.oregonlive.com/?classification=real+estate&temp_type=search&property=oregonlive.com&finder=hfrhttp://www.oregonlive.com/nowrentingguide/index.ssfPretty much any Trader Joes is a good Trader Joes. There's one on 39th just south of Powell, one on Burnside somewhere around 22nd or so and I'm sure there are more.
Trimet.org will give you an idea about the public transportation system in Portland. As Lydia Leftcoast once put it (paraphrasing), Portland figured out how to get people around town without a car. You can use your ticket or pass on Max (light rail system), the bus or in some parts of town the trolley system. Downtown Pdx is fareless square (though you can ride over the bridge to the first couple of Lloyd Center stops) and many employers offer a subsidized pass. Dh's company, for instance, offers a yearly pass for just over $100, a huge savings.
Portland is also very bike friendly if you like biking.
The downtown library is hands down the best, but many of their satellite libraries are excellent. I usually order things into my closest branch (which is a free service and maybe adds a day or two wait).
I have high-speed internet access and I live on the edge of Pdx. There is a farmers market downtown on the weekends and on the eastside on Wednesdays. Portland's Saturday Market is pretty much legendary.
If you're into books, then Powells Books is a must-see. Their Burnside store is the best.
I don't know a good chiropractor. There are plenty around. There is quite a few of them on Hawthorne from 39th down. Weird people tend to go to Hawthorne.
If you take a trip here, check out Kennedy School - it's an old elementary school turned into a brewpub by the McMenamin's brothers. It'll give you a reasonable idea of what that part of Pdx is like.