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OTC.
There were some problems w/addiction, but no more so than with other addictions, and the vast majority of people were pretty responsible in how they used most items. What was lacking was basic information, and dosing. My Grandmother, upon her passing, still had an old tin of cocaine in her med cabinet that was used for toothaches back in her day. It is a small tim and was dated 1913 impressed in the bottom. It has all kinds of turn of the century style art work, and while we disposed of the contents, the tin remains in family hands. She also had a green bottle labeled paregoric, you could shake it up and see the opium swirl through the alcohol...this after some 60 years! No one would be daft enough to try the stuff, but it shows just what could have been purchased not all that long ago.
Drug laws were enacted because of a perception that people would become addicted and thereafter be doomed to a life not worth living, theft, murder, sexual escapades etc. While these things were rare back before illegality, it took hold and the power that fear wields was felt under the law. Addiction to opiates at the time just before enactment, was about 0.7% in the US, alcohol addiction was about 9% of the population. Today, alcohol addiction is at about 10% of the population, w/abuse ranking at about 37%, but the opiate rate of addiction has only risen to 0.9%. There is still abuse at a higher rate, but true addiction remains relatively small.
On the other hand, cocaine addiction has risen markedly, and is at about 1.4% of the population, and abuse is at about 4.9%. These #'s stay pretty close to a baseline for most societies that have an addiction situation. The same thing rises for methamphetamine, but the effects of meth are incredibly difficult for the body to manage, and when one adds that how it is made effects it's purity and adds serious toxic chemicals like anhydrous ammonia, insecticides and battery acid, it is no wonder it is so devastating. Amphetamines of clinical purity, while being potentially additive, do not tear the body apart as the "street stuff" does.
Bottom line, no matter how many laws are passed, nor how a society frowns upon the use of mind altering substances, the one thing that laws DO do is increase the price for the substance. An increase in price means more profit, and therefore, the risk is acceptable in making/delivering the product. That tin of cocaine had a price stamped on it, "10 Cents", granted it was 1913, but it was also 1/2 oz. "pure" cocaine. FWIW, when opened, there was a lot of brown crystalline material in there, if she had used a penny's worth, I'd be surprised.
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