By Kiera Butler| Mon May. 16, 2011 2:30 AM PDT
Growing up in the '80s and '90s, I was the only kid I knew who was allergic to nuts. I remember explaining to a skeptical teacher why I couldn't eat the walnut brownies she'd brought for us one day. "But how do you know you won't like them if you won't even try?" she asked. Times have changed. You'd be hard pressed to find a gradeschool teacher now who wasn't well versed in EpiPens and anaphylactic shock; some school cafeterias are now nut-free zones. Indeed, nut allergies are on the rise. Last May, researchers at the Mt. Sinai School of Medicine found that the rate of childhood peanut allergy had more than tripled in recent years, up from .4 percent in 1997 to 1.4 percent in 2008.
No one is quite sure why allergies are becoming more common. One theory called the hygiene hypothesis speculates that the environment in developed countries is actually too clean: Since children no longer encounter the full array of germs and parasites they once did, their immune systems instead busy themselves reacting to pollens, molds, and certain proteins in foods. (In developing countries allergy rates are vanishingly tiny.) The allergy onslaught has also been linked to climate change; immunologists have long connected the rise in hay fever cases to global warming, and in 2008 an Ausrtralian researcher suggested (PDF) that climbing temperatures could be making certain foods more allergenic as well.
When I was diagnosed with nut allergies as a baby, my parents were told there wasn't much they could do about it, short of keeping me away from the offending foods and carrying an epinephrine shot in case I accidentally ate something nutty and developed an anaphylactic reaction. But in the past few years, pioneering immunologists have been experimenting with a new therapy for nut-allergic kids. Called oral immunotherapy or desensitization, it exposes patients to gradually increasing doses of nuts, with the aim of increasing their tolerance. The results so far have been promising. In the first study of the technique at Duke University, five out of seven participants were able to tolerate eating the equivalent of 13 peanuts by the end of the roughly two-year trial. Subsequent studies of other nuts, eggs, and milk, have shown similarly positive outcomes.
So will allergic kids soon be able to shed their EpiPens and MedicAlert bracelets? And will I get to order pad thai without all my friends chorusing to the poor waitress, "No nuts please!"?
http://motherjones.com/blue-marble/2011/05/nut-allergies-oral-immunotherapy-desensitization