ADA: Type 1 Diabetes Vaccine Fails to Show Benefit

[ellenrr]

6/27-San Diego- An antigen-based immunotherapy has failed to halt the progression of type 1 diabetes after one year, researchers reported here.

At one year, there were no differences in beta cell function, as measured by C-peptide levels, among recently diagnosed patients who had injections of glutamic acid decarboxylase (GAD) or placebo, Diane Wherrett, MD, of the Hospital for Sick Children in Toronto, and colleagues reported at the American Diabetes Association meeting and simultaneously online in The Lancet.

"Although antigen-based therapy is a highly desirable treatment and is effective in animal models, translation to human autoimmune disease remains a challenge," they wrote.

http://www.medpagetoday.com/MeetingCoverage/ADA/27304?pfc=101&spc=230

[trotsky]

1. Bummer.

Oh well, learn from the process and try again. Science marches on.