Question about vaccine adjuvants.

[pnwmom]

A new class of vaccine adjuvants is “mast cell activators.”

However, in people with autism spectrum disorders, “Mast cell activation may contribute to gut-blood-brain barrier disruption and brain inflammation.”

But every vaccine and every adjuvant is equally safe for all people. No matter what. Right?

:sarcasm:



http://mastcellmaster.com/documents/Autism-Exp-Opinion-Pharmacoth-8-09.pdf

Autism: an emerging ‘neuroimmune disorder’ in search of therapy
Theoharis C Theoharides†, Duraisamy Kempuraj & Lyn Redwood
†Tufts Tufts University School of Medicine, Department of Pharmacology and Experimental Therapeutics, Boston, Massachusetts, USA
Results/conclusion: Increased oxidative stress and immune dysregulation are present in ASDs. (Autism spectrum disorders) Mast- cell activation may contribute to gut–blood–brain barrier disruption and brain inflammation. No effective treatments have emerged.
SNIP
Much useful evidence has been produced over the last few years on ASDs <209>, but we now need to move from informational to transformational research if we are to develop novel effective treatments. Increased effort should be directed at understanding what might contribute to the pathogenesis of autism, rather than the neurological sequellae. Mast cells and CRH are involved in the regulation of BBB pathophysiology <139> and inflammation <105>. Enteroviruses, neuropeptides, stress hormones, and toxins could contribute through mast-cell activation, especially in subpopulations that are made vulnerable by their age and genetic make-up.
_________________________________________________________________________

http://www.nature.com/nm/journal/v14/n5/abs/nm1757.html

Article abstract
Nature Medicine 14, 536 - 541 (2008) 
Published online: 20 April 2008 | doi:10.1038/nm1757

Mast cell activators: a new class of highly effective vaccine adjuvants
James B McLachlan1,5, Christopher P Shelburne1,5, Justin P Hart1, Salvatore V Pizzo1, Rajen Goyal1, Rhea Brooking-Dixon1, Herman F Staats1,2,3 & Soman N Abraham1,2,4

Abstract
. . . . Collectively, these results define the MC as an integral sensory arm of the adaptive immune system. Moreover, they highlight MC activators as a new class of vaccine adjuvants, capable of inducing protective antigen-specific immune responses through needle-free routes of administration.

[Confusious]

1. Every scientific study has shown

There is no relationship between vaccines and autism.

The rate of autism is the same between the vaccinated and unvaccinated.

Maybe if you spent your time looking elsewhere, you would actually find the reason. Instead, you choose to waste your time beating a dead horse.

[pnwmom]

2. Have there been any studies of this new class of adjuvants

with regard to ASDs?

Or are you saying that any new adjuvant can be added to any vaccine without concern that the new ingredient could pose a risk to people with ASD or other susceptible populations?

[Confusious]

11. Basically, you're saying they cause autism

But autism was around before mast cell activators were in vaccines.

Autism was even around before there were a number of vaccines. indentified 1943, though there probably were cases before that, according to descriptions.

Instead oh looking at what could be the real problem, you waste time looking at bull because you can't admit you could be wrong.

and again, autism rates are the same in the vaccinated and unvaccinated.

keep beating that dead horse.

P.s. If you want to turn that around, I'll admit I was wrong if a majority of scientific studies support your case, but neither logic or science supports you.

[trotsky]

3. I'm pretty sure that the evil scientists in BIG PHARMA...

had hoped to sneak this under the radar. I mean, it was a huge blow to their plan to give autism to millions of kids when thimerosal got banned. This was going to be their replacement scheme! Thankfully you scoured the Internet and thwarted it. These evil scientists and their corrupt government lackeys are all muttering "Curses!" under their breath this morning - great job, pnwmom! :yourock:

[xchrom]

4. ...

:thumbsup:

[pnwmom]

5. Instead of addressing the actual issue -- new adjuvants that activate mast cells

and groups of people who have problems with their immune systems and mast cell activation, you take your usual route of personal attacks.

Great job, trotsky.

[trotsky]

7. Your OP contained a personal attack.

What else can you expect? Clearly you yourself aren't interested in an actual discussion, you only want to spread FUD about vaccines as always.

[pnwmom]

8. A personal attack? You think I addressed the OP to you personally?

And that it constitutes some kind of attack on you?

How strange. Get a grip.


:rofl:

[trotsky]

9. Nope, didn't say that.

But your post contained a comment that was directed at those who disagree with you, presenting their stance in a false manner.

[pnwmom]

10. Nope. No personal attack in any form.

It exists only in your imagination.

[trotsky]

14. What a coincidence!

Just like the autism-vaccine link exists only in yours!

[uppityperson]

6. unrec for "But every vaccine and every adjuvant is equally safe for all people. No matter what"

[SidDithers]

12. Has anyone, anywhere ever said that...

"every vaccine and every adjuvant is equally safe for all people. No matter what." :shrug:

Sid

[laconicsax]

13. The straw vaccinationist says it all the time.

You know, the one that secretly fills vaccines with evil, autism-causing adjuvants and forces poor, innocent parents to pump their children full of more autism-causing toxins under the guise of "disease prevention" and "public health."

[pnwmom]

15. It is frequently implied here -- every time people are criticized

merely for being concerned about risks of specific vaccines or adjuvants to specific groups people.

[Name removed]

16. Deleted message

Sub-thread removed by moderator. Click here to review the message board rules.

[mzmolly]

17. Makes me wax nostalgic

for mercury.

Thanks for sharing Pnwmom.