Enhancing the bioavailability of resveratrol by combining it with piperine

[Celebration]

http://www.ncbi.nlm.nih.gov/pubmed/21714124

Resveratrol (3,5,4'-trihydroxystilbene) is a phytoalexin shown to possess a multitude of health-promoting properties in pre-clinical studies. However, the poor in vivo bioavailability of resveratrol due to its rapid metabolism is being considered as a major obstacle in translating its effects in humans. In this study, we examined the hypothesis that piperine will enhance the pharmacokinetic parameters of resveratrol via inhibiting its glucuronidation, thereby slowing its elimination.................

snip..............

Our study demonstrated that piperine significantly improves the in vivo bioavailability of resveratrol. However, further detailed research is needed to study the mechanism of improved bioavailability of resveratrol via its combination with piperine as well as its effect on resveratrol metabolism.

[HysteryDiagnosis]

1. Bioperine is in my multi so that I may enjoy the benefits of a much smaller capsule than

would otherwise be necessary. That's what I think. Bioperine has been around as a stand alone product for many years, just now it is being given its due.

[ellenfl]

2. smaller capsule? i need that. kick for research. eom