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HysteryDiagnosis Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Oct-20-11 07:28 PM
Original message
Acne
First one thing: IBTL

This is a medical hypothesis. They hypothesize potential reasons for the development of acne. What you make of it is your business. That is all.

http://www.ncbi.nlm.nih.gov/pubmed/17448607
Med Hypotheses. 2007;69(5):1080-4. Epub 2007 Apr 19.
Acne vulgaris: nutritional factors may be influencing psychological sequelae.
Katzman M, Logan AC.
Source

START Clinic for Mood and Anxiety Disorders, University of Toronto, 790 Bay St., Toronto, Canada ON M5G 1N8. mkatzman@startclinic.ca
Abstract

Acne vulgaris is a distressing skin condition which can carry with it significant psychological disability. Patients with acne are more likely to experience anger and are at increased risk of depression, anxiety, suicidal ideation. Certain nutrients which have been implicated as influencing the pathophysiology of acne have also been identified as important mediators of human cognition, behavior and emotions. Zinc, folic acid, selenium, chromium and omega-3 fatty acids are all examples of nutrients which have been shown to influence depression, anger and/or anxiety. These same nutrients, along with systemic oxidative stress and an altered intestinal microflora have been implicated in acne vulgaris. It is our contention that certain nutritional factors, a weakened antioxidant defense system and altered intestinal microflora may interplay to increase the risk of psychological sequelae in acne vulgaris.

PMID:
17448607


http://www.ncbi.nlm.nih.gov/pubmed/21143923
Lipids Health Dis. 2010 Dec 9;9:141.
Clinical implications of lipid peroxidation in acne vulgaris: old wine in new bottles.
Bowe WP, Logan AC.
Source

Department of Dermatology, State University of New York Downstate Medical Center, Brooklyn, New York 11203, USA. wpbowe@gmail.com
Abstract

Acne vulgaris is a common dermatological disorder, one that is frequently associated with depression, anxiety and other psychological sequelae. In recent years there has been an increasing focus on the extent to which oxidative stress is involved in the pathophysiology of acne. Emerging studies have shown that patients with acne are under increased cutaneous and systemic oxidative stress. Indeed, there are indications that lipid peroxidation itself is a match that lights an inflammatory cascade in acne.

The notion that lipid peroxidation is a 'starter gun' in acne is not a new one; here we review the nearly 50-year-old lipid peroxidation theory and provide a historical perspective to the contemporary investigations and clinical implications.In addition, we present a novel hypothesis in which lipid peroxidation may be priming an increased susceptibility to co-morbid depression and anxiety in those with acne. The emerging research on the systemic burden of oxidative stress in acne sheds further light on the brain-skin axis. The recent findings also suggest potential avenues of approach for the treatment of acne via specific nutrients, dietary modifications, oral and topical interventions.

PMID:
21143923

PMCID: PMC3012032

Free PMC Article
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Cleita Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Oct-20-11 07:32 PM
Response to Original message
1. My personal experience, having suffered from acne, in
my youth, is that outbreaks depended on the climate. Living in desert and other low humidity regions, I got acne from the dry climate. Living in high humidity climates, it disappeared. :shrug: Go figure. I know my personal experience doesn't explain another person's experience so take it as anecdotal.
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HysteryDiagnosis Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Oct-20-11 07:34 PM
Response to Reply #1
2. Interesting and there is something here for you....
http://www.ncbi.nlm.nih.gov/pubmed/12227481

J Dermatol. 2002 Aug;29(8):484-8.
Seasonal variation in acne vulgaris--myth or reality.
Sardana K, Sharma RC, Sarkar R.
Source

Department of Dermatology & S.T.D., Lady Hardinge Medical College & Smt. Sucheta. Kriplani Hospital, New Delhi, India.
Abstract

A traditional opinion proposed by Western dermatologists is that acne improves in summer and worsens in winter. We studied 452 patiens with acne vulgaris and asked them about seasonal variation in their acne. A total of 229 patients (50.67%) complained of a seasonal variation; a significant proportion (56.33%) noticed an aggravation in summer, while 16.16% improved in summer and only 11.35% worsened in winter. Apparently winters did not affect the severity of acne in a majority of patients (64.20%). Significantly, a majority (80.62%) of patients noticed a summer aggravation due to sweating and increased humidity. Thus our study is at variance with the existing literature, with summer aggravation being the predominant complaint. We would like to propose that the increased temperature, marked humidity, and sweating might explain the results seen in our region.

PMID:
12227481
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Cleita Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Oct-20-11 08:24 PM
Response to Reply #2
4. See my post #3. It was meant to answer you here. n/t
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Cleita Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Oct-20-11 08:23 PM
Response to Reply #1
3. Maybe it's the sweating and not showering soon enough after?
I did most of my sweating in the dry, deserty climates and the moist climates that cleared up my skin were in the cooler but damp climates of the Northwest.
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