Interstitial cystitis and quercitin

[HysteryDiagnosis]

http://www.ncbi.nlm.nih.gov/pubmed/11272677?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

1: Tech Urol. 2001 Mar;7(1):44-6.Links
Treatment of interstitial cystitis with a quercetin supplement.
Katske F, Shoskes DA, Sender M, Poliakin R, Gagliano K, Rajfer J.

Division of Urology, Harbor-UCLA Medical Center, UCLA School of Medicine, Torrance, California, USA.

PURPOSE: Interstitial cystitis (IC) is a disorder of unknown etiology with few effective therapies. Oral bioflavonoid therapy utilizing quercetin recently proved to be clinically effective in men with chronic pelvic pain syndrome, a disorder with similarities to IC. We therefore tested in an open-label trial a quercetin-based supplement in patients with clinically proven IC.

MATERIALS AND METHODS: Twenty-two patients (5 men and 17 women; average age 53.1 years) with classically documented IC received one capsule of Cysta-Q complex (equivalent to 500 mg of quercetin) twice a day for 4 weeks. Symptoms were assessed before and after therapy by the IC problem and symptom indices as well as by global assessment of pain (range 0-10).

RESULTS: Two patients did not complete the study. In the remaining 20 patients, improvement was seen in all three parameters tested. After 4 weeks of treatment, the mean (+/- SEM) problem index improved from 11.3 +/- 0.6 to 5.1 +/- 0.7 (p = .000001), the mean symptom index improved from 11.9 +/- 0.9 to 4.5 +/- 0.5 (p = .000001), and the mean global assessment score improved from 8.2 +/- 0.4 to 3.5 +/- 0.4 (p = .000001). None of the patients experienced any negative side effects, and all but one patient had at least some improvement in every outcome measure.

CONCLUSION: Oral therapy with the quercetin supplement Cysta-Q was well tolerated and provided significant symptomatic improvement in patients with IC. Larger, randomized, placebo-controlled trials appear warranted based on these preliminary open-label results.

[cosmik debris]

1. THANK YOU!!!!

For posting the conclusion instead of just the title of the study.

[HysteryDiagnosis]

2. There was someone else in here in another thread who mentioned

IC.... I didn't want to hijack that thread but I hope the person in question notices this. Anyone remember who it was, it was just a couple of days ago... methinks.


ON EDIT: This site is hawking a quercitin based supplement while providing a primer on the subject of IC. I apologize that someone dares to market something to people that will probably help them... I truly do. Your mileage may vary.

http://www.farrlabs.com/condition/index/keyword/interstitial-cystitis.html
Read More

* Symptoms of Interstitial Cystitis
* Causes and Risks of Interstitial Cystitis
* Diagnosis of Interstitial Cystitis
* How To Address the Symptoms of Interstitial Cystitis
* Naturopathic Methods to Address the Symptoms of Interstitial Cystitis
* Special Concerns with Interstitial Cystitis
* Interstitial Cystitis Research
* Books on Interstitial Cystitis