Homeopathic Capsaicin-Based Nasal Spray Relieves Symptoms of Allergic Rhinitis

[Celebration]

http://www.newswise.com/articles/view/548536/

Researchers from Strategic BioSciences, together with investigators from the Institute for Asthma and Allergy (Wheaton, MD) reported that the new homeopathic product is safe and effective in relieving symptoms of allergic rhinitis. MucoAd™ is a mucoadhesive molecule (hypromellose) that prolongs contact with the nasal surface so that the nasal spray lasts longer and re-dosing is needed less frequently.

The double-blind cross-over study included 24 patients suffering from symptomatic, persistent allergic rhinitis who recorded the severity of their runny nose, itchy nose, stuffy nose and sneezing twice a day for a month. The capsaicin- MucoAd™ formula (Sinol-M™) was compared to the 1st generation product without MucoAd™ (Sinol™).

Capsaicin nasal spray reduced all symptoms, and symptom relief was achieved with less Sinol-M than Sinol – particularly at night, suggesting that Sinol-M might permit a better night’s sleep, free from rhinitis symptoms. There were no treatment related adverse events during the study and Sinol-M was associated with less subjective reports of discomfort.

The significance of the findings was summarized by Principal Investigator, Martha White, MD, who noted that, “These findings have important implications for the millions of people in the US who suffer from nasal allergies. Unlike the prescription nasal steroid sprays, this is an all-natural product that has now been demonstrated to provide clinical benefit and is available without a prescription.” The full results of this study will be published in a peer reviewed journal.

Sinol™ is registered as a homeopathic product in the US. Its principal active ingredient is capsaicin, which is derived from the hot pepper plant. The 2nd generation formulation, Sinol-M™, adds a patented mucoadhesive solution (MucoAd™) that prolongs the contact between a drug and the mucosa. Sinol-M™ is expected to become available in the US in March 2009.

[tridim]

1. I just shove two habaneros up my nose.

All kidding aside capsaicin is certainly an amazing substance, along with Cannabis it needs more research.

[EmilyAnne]

2. I use this. I call it my salt and pepper spray because it is saline and pepper.

I'm a dork.

[beam me up scottie]

3. Sinol is OWNED and MARKETED by pharmaceutical company Strategic BioSciences who paid for this study

What a shock.

Sinol USA to license MucoAd for the development of new formulations of Sinol Nasal SpraysStrategic BioSciences and Sinol USA announced today their intent to enter into a definitive agreement to develop and market a new formulation of SINOL Nasal Sprays with MucoAd™, a patented liquid mucoadhesive carrier.


FOR IMMEDIATE RELEASE
PRLog (Press Release) – Sep 19, 2008 – Washington, DC, and Newtown, CT --- Strategic BioSciences and Sinol USA announced today the signing of a Memorandum of Understanding (MOU) signifying their intent to enter into a definitive agreement to develop and market a new formulation of SINOL Nasal Sprays with MucoAd™. Under the terms of the MOU, Strategic BioSciences will license MucoAd™ to Sinol USA for use in the combined products on a worldwide basis.

***

Strategic Pharmaceuticals Company, LLC., doing business as Strategic BioSciences, is the joint venture of SRxA Holdings Inc, an affiliate of Strategic Pharmaceutical Advisors of Washington, DC and Fortune Apex Development of Tortola, BVI. Strategic BioSciences holds the exclusive global rights to MucoAd™. Patents for MucoAd™ have been granted in the United Kingdom and Singapore; and patents are pending in the United States and numerous countries and jurisdictions worldwide. Strategic BioSciences is headquartered in Washington, DC with offices in London and Hong Kong.

more about this for profit pharmaceutical company here: http://www.prlog.org/10119408-sinol-usa-to-license-mucoad-for-the-development-of-new-formulations-of-sinol-nasal-sprays.html

Discuss.

[SidDithers]

4. Big Vitamin sticking it to us again...

:hi:

Sid

[beam me up scottie]

6. They tested 24 whole people, Sid!

In a double-blind cross-over study! :rofl:

[cosmik debris]

9. That's twice as many as Wakefield tested

It gets hard to fake the data if you have too many people in the study.

[uppityperson]

7. Gee. I thought BigVita was above all this type stuff.

[Heddi]

8. Whoah. Back it up. beep beep beep

Are you suggesting...nay...outright SAYING that an alternative-healing company PAID FOR RESEARCH that happened to PROVE that ITS PRODUCT WAS BETTER THAN ANOTHER?

what planet am I on???

I just wanna make sure I got this straight....Sinol is OWNED by the company that did a RESEARCH STUDY (double cross astigmatism tested no less!) that showed that SINOL (the product the company owns) is better than other products (that aren't owned by the company that did the research) at helping sinus pain (note SINol's name....any coinicidence that a product with the name SIN has to do with SINuses?)

Surely there is some hidden research that Strategic BioSciences is an anagram of GLAXOSMITHKLINEMERK. Check it before you wreck it. I GUARANTEE you that within the next 10 hours there will be SOME post that links Strategic BioSciences with SOME CDC, FDA, big Pharma connection, and THAT'S THE ONLY REASON why a STUDY WAS BOUGHT AND PAID FOR BY A COMPANY THAT MARKETS THE PRODUCT BEING TESTED AND SUPPOSEDLY VETTED because, as we all know, supplement and vitamin companies and their marketers are angels full of morals and ethics that give their products away for free and never take a profit. Oh, and Jesus is on their board of directors SO TAKE THAT SHILL

[Maryanne123]

10. Sinol Nasal Spray

I use Sinol and have for about a year now. I didnt need a clinical study to know this product works. My allergy systmes including congestion is relieved in minutes. I recommend Sinol to everyone with allergies as I am a pharmacist at Rite Aid and we sell Sinol at Rite Aid.

[Celebration]

11. Is Sinol-M available yet

Or do you know when it will become available?

Thanks for telling your experience.

[Heddi]

12. wait, you're a pharmacist

and you can't even spell SYMPTOMS, or SYSTEMS (or whatever in the hell you're trying to spell) correctly???

puh. leeze.

"I use Sinol and have for about a year now. I didnt need a clinical study to know this product works. My allergy systmes including congestion is relieved in minutes. I recommend Sinol to everyone with allergies as I am a pharmacist at Rite Aid and we sell Sinol at Rite Aid."

Let me know where you went to Pharmacy school so I can avoid all pharmacists that went to that school......

[uppityperson]

20. Now now now, maybe Riteaid pharmacists have "systmes"?

"I recommend the product I sell to everyone! Oh yes, did I tell you you can buy this from me? systmes rule!"

[Heddi]

21. you know, I use Rite Aid for my various Prescription Pharmaceutical Needs

It's right up the street from me, across from the bus stop, and is very convenient.

I'll have to ask the nice lady behind the pharmacy counter what Systmes are, and whether they carry them for consumption by the general population.

In a funny and rather unrelated note, a few years ago I worked with a relatively new RN, and we did paper charting. I had the patient the day after this relatively new nurse did, and i was reading his note, and it said something to the effect of:

"Patient's BP at 20:00 103/78, at 24:00 210/100. Pt was ASYSTEMATIC at the time" ha ha ha. Instead of Asymptomatic, A-SYSTEMATIC ha ha ha he had no systems with that blood pressure heh.

[EvolveOrConvolve]

16. Anecdotal evidence kicks ass!

It's almost as good as real science! :sarcasm:

[ayeshahaqqiqa]

18. Welcome to DU!

Thanks for this information.

[muriel_volestrangler]

22. I always find a recommendation from a member who joined just to make it

for a commercial product, and kicked a thread that was more than a month old to do it, is one I can trust completely. There's no suspicion whatsoever that it's just a rather illiterate marketeer who has done a web search for the product they've been told to push on the 'net, and who is claiming to be a pharmacist in a desperate attempt to gain credibility.

As a pharmacist, have you any comment about the study that shows that the new product is better than the one you use? Or are you telling us to ignore the study, and that your old product is perfect in every way?

Is masquerading as a pharmacist actually an offence anywhere, does anyone know? I suppose if you're using a pseudonym it may not be.

[Manifestor_of_Light]

5. I use this stuff for sinus congestion.

I get it from Aromatherapeutix.
It's a blend of oils. I dilute it in carrier oil, and put two drops on a Q-tip and then smear it in my nostrils. It's very helpful for congestion.


http://www.aromatherapeutix.com/catalog/category18/product36/page100



:D Works well!!!

[Crunchy Frog]

13. Is this actually homeopathic? I thought that in homeopathic

the "active" ingredient was at such a low concentration as to be practically non-existant. Sorry to be nitpicking, but I think the term is often misused.

[Why Syzygy]

15. It is often misused.

I wondered the same. There is disagreement about what "non-existant" {sic} means.

According to the website, Capsicum is the only ingredient that is homeopathic (4x).

Sinol's All Natural Ingredients

Aloe Vera Extract, Eucalyptus Oil, Rosemary Extract, Sea Salt, Vitamin C and Capsicum 4x
http://www.allergy-relief-sinol.com/about_us.php

[semillama]

14. Not certain about the study

but here's a link to the study at clinicaltrials.gov:

http://clinicaltrials.gov/ct2/show/study/NCT00825656


Obviously, it's an interesting result if true, but the actual results are not posted yet at clinicaltrials.gov.

What concerns me is that it is unclear if the double blind study looked at treatment with Sinol-M vs a saline spray with no medication, or if it was a study of patients getting Sinol-M vs. those getting Sinol, with no placebo control.

[beam me up scottie]

19. Bingo. "it was a study of patients getting Sinol-M vs. those getting Sinol, with no placebo control"

The double-blind cross-over study included 24 patients suffering from symptomatic, persistent allergic rhinitis who recorded the severity of their runny nose, itchy nose, stuffy nose and sneezing twice a day for a month. The capsaicin- MucoAd™ formula (Sinol-M™ ) was compared to the 1st generation product without MucoAd™ (Sinol™ .)

24 patients, no placebo. Just another internet alt-med pharmaceutical corporation woofomercial posted in DU's Health Forum.

[ayeshahaqqiqa]

17. Thanks for this information

I'm forwarding it to my homeopathic physician. She's always looking for the latest information on this. It seems that there are more and more people having problems with allergies these days. I'm thinking it is caused by the rise in pollen due to global warming.

[Mamacrat]

23. Itching

I heard an interesting interview on NPR yesterday about itching and that capsicum can help relieve it. So, I was interested in this nasal spray until I read it also has eucalyptus oil. I'm very allergic to eucalyptus. Otherwise, it sounds like it's worth a try.

[Warpy]

24. So does salt water spray

Both will dislodge pollens and/or molds from nasal mucosae.