14 March 2006
NewScientist.com news service
Roxanne Khamsi
Elderly patients taking certain drugs to lower their blood pressure appear to have a markedly reduced risk of Alzheimer’s disease, researchers report. Results from their short-term study suggest that some of these medications could slash this risk by up to 70%.
Previous research has shown that high blood pressure, also known as hypertension, can increase a person’s chances of developing Alzheimer’s disease. Doctors commonly prescribe patients medications such as diuretics, which cause the kidneys to excrete water and salt, to lower blood pressure. Beta-blockers, which slow the heart rate and widen blood vessels, also work against hypertension.
Potassium levelsOverall, antihypertensive drugs appeared to reduce the risk of Alzheimer’s disease by 40%. But the figure jumped even higher – to 70% – when they looked at a specific class of diuretics that have the desired effect on the kidney while maintaining higher bodily levels of the nutrient potassium.“We would not want people to interpret these findings as a recommendation to go out and start taking antihypertensive drugs,” Zandi says, adding that further studies are necessary to back up the results.
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