By Erin Richards | February 20th 2009 11:41 AM |
The floodgates have opened, and through it rushes advances in stem cell research. It seems that every day, another effort makes a push forward for medical stem cell therapy.
Earlier this week, a team of research scientists published a study evaluating long term clinical results of treating patients with Parkinson’s disease with autologous neural stem cells. The results of the study demonstrated that stem cells from cerebral tissue could form differentiated neurons and could produce dopamine and reverse symptoms of Parkinson’s. Restored GABA and dopamine signals can restore and provide long term motor improvement.
These images show malfunctioning nerves consistent with Parkinson's. The second image (below) shows increasing activity after implantation. "18-Fluoro-DOPA Positron Emission Tomography Studies. (a) Pre transplant uptake study showing decrease nerve terminal density in the striatum, worse on left (right on picture), consistent with Parkinson’s disease. (b) Post transplant study with increase activity of marker at the site of micro-injections in left putamen." (Levesque et. al.)
According to lead author, Michel F. Levesque, MD, FRCS(C), FACS, "We have documented the first successful adult neural stem cell transplantation to reverse the effects of Parkinson's disease and demonstrated the long term safety and therapeutic effects of this approach."
more:
http://www.scientificblogging.com/erin039s_spin/another_breakthrough_neural_adult_stem_cells