Dr. Sinatra is a cardiologist who takes a very proactive stance toward heart health aside from the usual ramming of prescriptions down patients' throats.
He recommends a regimen of supplements. I've started on some of them, and have felt much stronger and healthier as a result.
And he has a whole section on cholesterol. Here's a bit of the text.
Lower Your Cholesterol Naturally
You can reduce your cholesterol level naturally-regardless of how high it is — if you:
1. Follow my PAMM diet, avoiding saturated fats and emphasizing cholesterol busters like oat bran, soy products, fresh garlic, and phytosterol-rich foods such as olive oil, nuts, flax and other seeds, and beans. Phytosterols are plant nutrients that inhibit the body's ability to absorb dietary cholesterol.
2. Take these targeted nutritional supplements in addition to a good multi-vitamin:
Niacin, which is very effective at promoting healthy levels of cholesterol and Lp(a), another "toxic blood" risk factors for heart disease. Since therapeutic levels of niacin can cause an unpleasant flushing sensation and headache, gradually increase your dosage over several weeks or use the flush-free form of niacin, inositol hexaniacinate. Dosage: 100 mg twice daily, increasing to 1,000 mg daily. Or, ask your doctor about Niaspan, a source of niacin I like, which requires a prescription.
Coenzyme Q10 (CoQ10), the nutrient I can't imagine practicing medicine without. CoQ10 supports healthy HDL and prevents the excess oxidation of LDL. Dosage: 45-90 mg of liquid, water soluble CoQ10 daily.
Policosanol, derived from the wax of sugar cane, is very effective for lowering total and LDL cholesterol levels. Take 10-20 mg after dinner.
3. For extra cholesterol-lowering support, consider adding several or all of my other hand-picked favorites:
L-carnitine (500-1,000 mg daily), which works synergistically with CoQ10 to support healthy cholesterol.
Tocotrienols (50-100 mg daily), more recently-studied forms of vitamin E that help lower cholesterol (which standard d-alpha tocopherol vitamin E does not do) and provide greater antioxidant protection than regular vitamin E.
Fish oil (500-1,000 mg daily) lowers blood triglyceride levels, may elevate HDL, and helps support heart health.
Garlic (dosage varies depending on the product) reduces triglycerides and LDL cholesterol, and prevents LDL oxidation. In addition to using fresh garlic in your cooking, you can also take a therapeutic dose of garlic in supplement form. Look for garlic supplements standardized to allicin potential or yield, and aim for 6,000 mcg of allicin per day.
Pantethine (500 mg, 3 times daily), a component of vitamin B-5, or pantothenic acid, supports healthy HDL, LDL, and triglyceride levels.
Probiotics (2 capsules a day, between meals) or "friendly bacteria" such as L. acidophilus, S. thermophilus, E. faecium, and the Bifidobacterium family help promote healthy cholesterol by converting it into a less absorbable form and sending it down the gut so it can be eliminated.
Rutin and Hesperidin, antioxidants which help to strengthen the lining of the arteries and maintain their health by fighting free radicals and supporting collagen - as well as helps to reduce LDL cholesterol oxidation. These types of bioflavonoids are typically found in foods, like fruits and vegetables, especially in the white pith or peel of citrus fruits and peppers that contain vitamin C.
Phytosterol Esters, help reduce the absorption of dietary cholesterol in the small intestine, promoting normal cholesterol levels and HDL:LDL cholesterol ratios. Phytosterol Esters are waxy, oily, fat-like compounds found in many fruits, vegetables, vegetable oils, nuts, seeds, and legumes. Although relatively abundant in our foods, we obtain very little from the diet due to modern food preparation techniques that destroy the sterol esters found in plants. Daily consumption of at least 1.3 grams of phytosterol esters in two meals as part of a diet low in saturated fat and cholesterol may reduce the risk of heart disease. Cholesterol Solutions contains 0.65 grams of per serving.
Both black and green tea contain catechins or polyphenols, which help lower and cholesterol and improve lipid metabolism. On average, green tea contains half the caffeine of black tea. Drink a cup or two of green tea daily. Green tea extracts are also available in supplement form.
Interactions you should know about
Since both garlic and fish oil have a mild blood-thinning effect, do not take either one with blood-thinning medications such as Coumadin (warfarin), heparin, Plavix (clopidogrel), or Trental (pentoxifylline).
Taking garlic with ginkgo or high-dose vitamin E can cause a risk of bleeding problems.
Taking fish oil by itself does not seem to cause bleeding problems.
Never take aspirin and ginkgo together.
http://www.drsinatra.com/MainSite/HealthCenter.aspx?Healthcenter=JRCA_HC%20Cholesterol