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Celebration Donating Member (1000+ posts) Send PM | Profile | Ignore Sun May-03-09 11:47 AM
Original message
Diabetes type 2 cured by surgery
http://www.abc.net.au/rn/scienceshow/stories/2009/2554683.htm

Type 2 diabetes accounts for 90-95% of diabetes. Despite 20 years of research, the problem has not been solved. There are medicines to take, but when onset is early, patients will die early despite the many treatments. People think of diabetes as a chronic, progressive incurable disease. Richard Stubbs says this is wrong. He performs gastric bypass surgery for severely obese people. These people certainly lose weight. But in addition, if diabetic, their diabetes also stops. Richard Stubbs claims diabetes is a disease of the gut. His hypothesis is the portion of the gut bypassed in surgery is producing a hormone, currently unknown, which is antagonistic to insulin. Richard Stubbs is trying to identify the hormone, and when this happens, it can be targeted by drugs.


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ananda Donating Member (1000+ posts) Send PM | Profile | Ignore Sun May-03-09 12:08 PM
Response to Original message
1. Wow. How interesting!
nt
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TZ Donating Member (1000+ posts) Send PM | Profile | Ignore Sun May-03-09 12:14 PM
Response to Original message
2. QUACK!
Of course someone who performs gastric surgery would have no motive in claiming he can cure something! Ignoring of course the known fact that NOT ALL type 2 diabetics are obese. And people wonder why snake oil merchants survive I his county.it's because people like you lack critical thinking skills and don't understand that msm is fucking stupid when it comes to science reporting.



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chimpyisstillsatan Donating Member (252 posts) Send PM | Profile | Ignore Sun May-03-09 12:19 PM
Response to Reply #2
6. obese people with type 1 diabetes can respond similarly after surgery.
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BadgerKid Donating Member (1000+ posts) Send PM | Profile | Ignore Sun May-03-09 12:14 PM
Response to Original message
3. Maybe he means glucagon.
If so, maybe diabetes could be viewed as a pancreas issue.
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chimpyisstillsatan Donating Member (252 posts) Send PM | Profile | Ignore Sun May-03-09 12:16 PM
Response to Original message
4. I believe this
I've seen some of this data, it's a very real phenomenon, but I am not convinced Stubbs is on the right track as to the cause. The effects of surgery are often independent of caloric intake or body weight and can happen almost overnight. Too bad we can't do sham surgery on obese patients to sort this out. My suspicion is that the anaesthesia and surgical stress would be enough to affect the disease.
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Celebration Donating Member (1000+ posts) Send PM | Profile | Ignore Sun May-03-09 12:27 PM
Response to Reply #4
10. listen to the segment
He talks about the effects of the two different types of surgery--the "band" obesity surgery, vs. gastric bypass. It's pretty interesting.
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chimpyisstillsatan Donating Member (252 posts) Send PM | Profile | Ignore Sun May-03-09 12:37 PM
Response to Reply #10
13. will do, thanks (nt)
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jaysunb Donating Member (1000+ posts) Send PM | Profile | Ignore Sun May-03-09 12:18 PM
Response to Original message
5. Lose the weight...lose the disease
It's pretty straight forward. ( in most cases )
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chimpyisstillsatan Donating Member (252 posts) Send PM | Profile | Ignore Sun May-03-09 12:21 PM
Response to Reply #5
8. not everyone can lose weight
what about the mentally ill? People on atypical antipsychotics? Shouldn't all options be available, or at least considered?
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Celebration Donating Member (1000+ posts) Send PM | Profile | Ignore Sun May-03-09 12:28 PM
Response to Reply #5
11. there are many Type 2 diabetes patients
With normal weight. It just isn't that straightforward.
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jaysunb Donating Member (1000+ posts) Send PM | Profile | Ignore Sun May-03-09 09:35 PM
Response to Reply #11
15. I guess I'm projecting my own situation
After losing about 20 pounds I was able to get down to 5 mg of glyberide. The doctor felt if I lost 30 more there'd be no need for any meds...just excersise and low fat diet.

Needless to say, I gained back 10 and am back up to 10 mgs of glyberide and actos.

I should have noted that all cases are not the same.
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tkmorris Donating Member (1000+ posts) Send PM | Profile | Ignore Mon May-04-09 02:34 AM
Response to Reply #5
17. Completely untrue
My wife is actually underweight, given normal guidelines, but guess what? Yep, still diabetic.
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jody Donating Member (1000+ posts) Send PM | Profile | Ignore Sun May-03-09 12:20 PM
Response to Original message
7. Fascinating, remember how the medical community first rejected the findings by two Australian
scientists, Robin Warren and Barry J. Marshall, that helicobacter pylori was a causative factor for ulcers?

What a tremendous finding if Stubbs is correct.
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TNDemo Donating Member (1000+ posts) Send PM | Profile | Ignore Sun May-03-09 12:25 PM
Response to Original message
9. What about people who aren't obese?
My dad weighed about 150 and my mom about 120 and I am 130ish, all of us with type II diabetes (they are gone now). So how would bypass surgery cure our diabetes?
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Celebration Donating Member (1000+ posts) Send PM | Profile | Ignore Sun May-03-09 12:30 PM
Response to Reply #9
12. well
1. He wants to identify the gut hormone and develop drugs to combat it.

2. He says that in South America they are trying to develop an operation for normal weight Type 2s based on these principles.
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TNDemo Donating Member (1000+ posts) Send PM | Profile | Ignore Sun May-03-09 12:50 PM
Response to Reply #12
14. Seems like the loss of fat is what would be curing the diabetes in
gastric bypass. But what do I know...really.
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Lex Donating Member (1000+ posts) Send PM | Profile | Ignore Sun May-03-09 11:17 PM
Response to Reply #14
16. No, it happens immediately post-surgery
as I understand it. The weight loss happens over time.

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TNDemo Donating Member (1000+ posts) Send PM | Profile | Ignore Mon May-04-09 07:52 AM
Response to Reply #16
18. But they are hardly eating anything right after surgery,
which would naturally lower the glucose. I guess my job is devil's advocate today.
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Celebration Donating Member (1000+ posts) Send PM | Profile | Ignore Mon May-04-09 08:08 AM
Response to Reply #18
19. that's okay
Good to be skeptical. Hopefully a little time and research will sort things out. Obviously some of the doctors feel that it is an effect of the surgery itself rather than the secondary effect of eating less. I think the idea is definitely worth pursuing.
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