Dev Sci. 2006 Jan;9(1):46-50.
Preference for consonance over dissonance by hearing newborns of deaf parents and of hearing parents.
Masataka N.
Japan Science and Technology Agency, Saitama, Japan.
Behavioral preferences for consonance over dissonance were tested in hearing infants of deaf parents and in hearing infants of hearing parents when they were 2 days old. Using a modified visual-fixation-based, auditory-preference procedure, I found that both 2-day-old infants of deaf parents and those of hearing parents looked longer at a visual stimulus when looking produced the original version of a Mozart minuet as opposed to a version altered to contain many dissonant intervals. The relative magnitude of such preference did not significantly differ whether their parents were deaf or hearing. Infants prefer consonance over dissonance, and the preference is present from birth and is not dependent on any specific prenatal or early postnatal experience
PMID: 16445395
Neurol Res. 2005 Dec;27(8):791-6.
Long-term enhancement of maze learning in mice via a generalized Mozart effect.
Aoun P, Jones T, Shaw GL, Bodner M.
MIND Institute, 1503 South Coast Drive, Costa Mesa, CA 92626, USA.
OBJECTIVES: An animal model of the 'generalized Mozart effect' (GME) - enhanced/normalized higher brain function in response to music exposure - has been established. We extend those results in two studies using another species (mice). Study 1: (1) maze testing after music exposure was extended to a minimum of 6 hours; (2) no exposure to music in utero. Study 2: (1) music exposure time further reduced; (2) maze testing extended to 24 hours. METHODS: Study 1: two mouse groups were exposed to music continuously for 10 hours per day for 10 weeks (Group I: Mozart's Sonata K.448, Group II: Beethoven's Fur Elise). After 10 weeks, the ability to negotiate a T-maze was assessed (recording working time in maze, number of errors). Maze ability was tested 6 hours following the last music exposure. Study 2: two mouse groups were exposed periodically to music (58% silence) 10 hours per day for 10 weeks. Experiments after 10 weeks examined the groups' abilities to run the maze (recording working time/errors). Experiments were conducted 24 hours following the last music exposure. RESULTS: The Mozart group exhibited significant enhancements compared with the control mice in both studies, i.e. significantly lower working time (p<0.05) and committed fewer errors. DISCUSSION: Observation of GME in another species supports its generality for the mammalian cortex. The absence of a GME in fMRI studies for the control music also indicates a neurophysiological basis. With extended exposure, GME is a long-term effect, indicating potential clinical importance. It has been demonstrated that GME reduces neuropathological spiking significantly in epileptics. We discuss the relevance of this study for epilepsy treatment.
PMID: 16354537
Behav Med. 2003 Spring;29(1):15-9.
Listening to mozart reduces allergic skin wheal responses and in vitro allergen-specific IgE production in atopic dermatitis patients with latex allergy.
Kimata H.
Department of Allergy at Ujitakeda Hospital, Kyoto, Japan.
In atopic dermatitis patients with latex allergy, listening to Mozart reduced skin wheal responses induced by latex, but not by histamine, whereas listening to Beethoven failed to produce similar results. Listening to Mozart also decreased in vitro total IgE and latex-specific IgE production with concomitant skewing of the cytokine pattern toward the Th1 type, that is, an increase in Th1 cytokine production and decrease in Th2 cytokine production by peripheral blood mononuclear cells, whereas listening to Beethoven failed to do so. These results suggest that therapy using specific types of music may be an effective treatment of allergic diseases.
PMID: 14977243