http://www.cancerpage.com/news/article.asp?id=9613 NEW YORK (Reuters Health) - In men, low levels of vitamin D appear to be associated with increased cancer incidence and mortality -- particularly cancers of the digestive system -- researchers report in the April 5th issue of the Journal of the National Cancer Institute.
Co-author of an accompanying editorial, Dr. Gary G. Schwartz of Wake Forest University, Winston-Salem, North Carolina told Reuters Health that "these observations add to a growing body of evidence that vitamin D, whose major source is casual exposure to sunlight, may play important roles in the natural history of many cancers."
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To help quantify its effect, the researchers first correlated determinants of vitamin D exposure with serum levels in some 1000 men. Items involved were dietary and supplementary vitamin D, skin pigmentation, adiposity, geographical residence and leisure-time physical activity, and hence sunlight exposure. The researchers then computed vitamin D levels for 47,800 men in the Health Professionals Follow-Up Study.
An increment of 25 nmol/L in the predicted blood level of vitamin D was associated with a 17 percent reduction in total cancer incidence, a 29 percent reduction in total cancer mortality and a 45 percent reduction in digestive system cancer mortality.