Discovery Has Potential to Boost Anti-Breast Cancer Drug Tamoxifen's Effectiveness

[HuckleB]

http://www.sciencedaily.com/releases/2010/10/101015105821.htm

"Scientists in London have found a potential new way of boosting the effectiveness of the anti-breast cancer drug, tamoxifen.

...

Tamoxifen is given to most women for five years after they are first diagnosed with breast cancer to help prevent the disease recurring.

However, some breast cancers are resistant to the drug, or can develop resistance over time, allowing the cancer to recur or continue growing. Professor Isacke's discovery could lead to new drugs that counteract this resistance.

...

In their current paper, published in the cancer journal Oncogene, they show that when a protein called RET is switched on, it can activate the oestrogen receptor in the absence of any oestrogen.

..."

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Another step forward. Hopefully it leads to additional steps forward.

:hi:

[xchrom]

1. that would be very cool. nt