it is getting to the nitty-gritty of what the health care reforms will mean. We ration health care now by cost, which is unfair, not progressive and inefficient. The inefficiency comes when people who cannot afford continuing care find themselves using a hospital emergency room and transfering much bigger costs onto a public system.
The article talks about hard choices like whether or not drugs that cost $54,000 for a dose and may result in six extra months of "life" for a terminal patient are worth it. ("Life" because the quality of the life under consideration in terms of mobility, mental agility, dependence and so forth are not factored in.) At some point in time, we have to have this debate. We are already rationing health care, how are we going to ration it in the future? Who will get it and how are we going to pay for it. This debate will be more intense the greater the public option is, btw. This is something not currently in the debate.
There was an
http://www.boston.com/news/world/latinamerica/articles/2009/06/14/one_girls_hope_a_nations_dilemma/">interesting article in the Boston Globe a few weeks back about how "miracle" drugs for serious but rare ailments are marketing in developing, poor countries. I think this article should be read by everyone because the pressures brought to bear on the Costa Rican system will, in one form or another, be brought to bear on our system, even under the sacred "public option." We are not having the big debate we need to have, we are having a sideshow debate right now.
But the doctor had another piece of news. There was a drug that might halt Tania's suffering and perhaps even reverse the toll of her disease. The drug was called Cerezyme.
For Jose and his family, it was as though a hand had reached down to answer their prayers. But in that moment, something else had happened as well: The Cambridge drug company Genzyme had just found its first potential patient in Costa Rica. And now that it had found one, it would supply the drug to Tania, but at an astonishing cost - $160,000 a year, possibly for the rest of her life.
This was far more money than the Costa Rican government had ever paid for a drug, and Genzyme would not bend on the price. The country's health officials were forced to weigh the prospect of a healing gift for one girl against the needs of a nation struggling to care for millions.
Should Tania get the drug?
What unfolded in that village was a dramatic example of the hard choices often forced by the inventions and ambitions of the biotechnology industry, an increasingly important part of global healthcare and a critical growth sector for Massachusetts. Its high-priced cures are creating both great wealth and great moral dilemmas, one new drug, one new patient at a time.
SNIP
If Cerezyme was not just another drug, the Cambridge firm that manufactured it did not consider itself just another drug company. When Genzyme Corp. first introduced a bioengineered drug for Gaucher (pronounced GO-shay) disease in the 1990s, the very idea seemed almost absurd to most people in the pharmaceutical industry. It was expensive to manufacture, there were vanishingly few known patients, and it wasn't clear how you could sell enough of it to recoup research costs, never mind make a profit.
Genzyme's solution, elegant in its way, was to set a price high enough to earn a substantial profit no matter how small its pool of patients. Then the company surprised the medical world - and its investors on Wall Street - by showing that American health insurers could be persuaded to pay the six-figure price tag. And with the only effective treatment for Gaucher disease, Genzyme never needed to lower the price, even as production efficiencies raised profit margins on the drug to as much as 90 percent.
The drug started to bring in tens of millions of dollars a year, then hundreds of millions. Today this one drug, prescribed for about 5,000 patients, has transformed Genzyme and its chief executive, Henri Termeer, into one of the great success stories of biotechnology, fueling its expansion into a $16 billion company with offices and factories worldwide.
By the early 2000s, Genzyme had reached most of the known Gaucher patients in the United States, so it had begun pushing outward to new markets. Genzyme created divisions within the company to find overseas patients; it hired experts to cajole balky governments into paying for the patients' Cerezyme doses. Some of the company's successes were extraordinary: hundreds of patients in Brazil. Patients in Taiwan, Kuwait, and Bulgaria. The government of Libya's Colonel Moammar Khadafy pays for Cerezyme for a handful of patients.
As it notched these successes, the company stayed largely under the radar of public health activists who were pushing drugmakers to discount AIDS drugs and other lifesaving medications whose retail prices were financially out of reach to many governments.