I listen to the following shows either daily, or every time they're updated:
The Stephanie Miller Show
http://www.stephaniemiller.comBreakroom Live with Marc Maron and Sam Seder
http://airamerica.com/breakroomliveThe Limbaugh Lie of the Day
http://www.conceptualguerilla.com/?q=view/audio/limbaughlieThe Thom Hartman Show www.thomhartmann.com
Skeptoid
http://skeptoid.comThe Progressive Point of View
http://mefeedia.com/feeds/15507/progressive-point-of-viewJim Hightower's Common Sense www.jimhightower.com
The Amazing Show with James Randi www.itricks.com/randishow
The Onion Radio News www.theonion.com/content/radionews
The Best of The Left Podcast www.bestoftheleftpodcast.com
Science@NASA Podcast www.science.nasa.gov/podcast.htm
Also very good:The Rachel Maddow Show Podcast
http://www.podcastdirectory.com/podcasts/1143Countdown with Keith Olbermann Podcast
http://podcast.msnbc.com/audio/podcast/MSNBC-Countdown.xmlThe Young Turks First Hour
http://www.podcastalley.com/see_comments.php?pod_id=45179Democracy Now
http://www.democracynow.org/Capitol Steps: Politics Takes a Holiday www.capsteps.com/radio
Humanist Network News humaniststudies.org/podcast/
Truth-Driven Thinking Podcast www.truthdriventhinking.com/podcast.htm
Liberal Religious Community www.uucb.org/sermons/rss.xm
Point of Inquiry www.pointofinquiry.org
The Real Time with Bill Maher Podcast
http://www.hbo.com/apps/podcasts/podcast.xml?a=2The Progressive Geek progressivegeek.com/?feed=podcas
Slate Magazine Daily Podcast www.slate.com/podcast/